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Monday, October 8, 2007

Some interesting facts....

- 60-80 tumour cells can initiate angiogenesis,
- 100 tumour cells may initiate neovascularisation,
- In vivo, cancer cell move at high speed of up to 15 μm in a minute,
- The minimum diameter of capillaries where cancer cells are able to migrate is
approximately 8 μm/h,
- Non-dividing cancer –cells in capillaries over 8 um in diameter could migrate up to 48.3
μm/h,
- Micrometastasis occur either with 1 cells or fewer than 10 tumour cells,
- The GFP+ cells migrated dorsoventrally at an average speed of 9.8 ± 2.1 µm/h,
- Mouse epidermal stem cells have been shown to migrate 1 mm in 24 hours,
- Embryonic cortical neural stem cells migrate at an average speed of 1.5 ± 1.8 μm/h,
- The migration of transplanted cells labeled with magnetic nanoparticles migrated towards
the ischemic parenchyma at a mean speed of 65 μm/h,
- In pre-metastatic microenvironment, the mean speed of migration of EGF-treated cells
on LN5 was 48 ± 14 μm/h,
- The average rate of migration of the mutant cells (example, myosin) was 1.8 μm/h,
- invasive glioma cells migrate at an average speed on tissue-culture plastic surfaces was
12.5 μm/h,
- colorectal cancer tumor cell migration varied from 5.6 plus/min 2.5 μm/h (demonstrated
in Panc-1, Human pancreatic carcinoma, epithelial-like cell line),

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